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Species: Human Sample Types: Whole Cells Applications: Neutralization Crucial role of IL1beta and C3a in the in vitro-response of multipotent mesenchymal stromal cells to inflammatory mediators of polytrauma. Species: Mouse Sample Types: In Vivo Applications: Neutralization Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.

Species: Human Sample Types: Whole Cells Applications: Isotype Control The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck. Species: Mouse Sample Types: Whole Cells Applications: Flow Cytometry Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling.

Normal Goat IgG Control

Species: Rat Sample Types: In Vivo Applications: Control Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia. Species: Rat Sample Types: Whole Cells Applications: Neutralization Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability.

Species: Mouse Sample Types: In Vivo Applications: Neutralization Control Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage. Applications: Isotype Control Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells. Species: Mouse Sample Types: In Vivo Applications: Neutralization Interleukin and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.

Species: Human Sample Types: Recombinant Protein Applications: Co-Immunoprecipitation Blimp1 Prdm1 prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence. Species: Mouse Sample Types: Tissue Homogenates Applications: Immunoprecipitation Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Species: Mouse Sample Types: Whole Cells Applications: Neutralization Control Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes.

Species: Human Sample Types: Whole Cells Applications: Control Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model. Species: Mouse Sample Types: In Vivo Applications: Control The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Species: Human Sample Types: Whole Tissue Applications: Control Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc.

Species: Mouse Sample Types: In Vivo Applications: Control The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy. Species: Human Sample Types: Whole Cells Applications: Control Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Lung Cell Mol. Species: Mouse Sample Types: Whole Tissue Applications: Control Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.

Species: Human Sample Types: Whole Tissue Applications: Control Relationship between complement membrane attack complex, chemokine C-C motif ligand 2 CCL2 and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization. Allergy Clin. Species: Human Sample Types: Whole Cells Applications: Control A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Species: Mouse Sample Types: Whole Tissue Applications: Control Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.

Species: Mouse Sample Types: Whole Cells Applications: Control Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.

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Species: Human Sample Types: Whole Cells Applications: Control Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis. Species: Mouse Sample Types: In Vivo Applications: Control Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukinactivated inducible nitric oxide synthase-related pathway.

Species: Mouse Sample Types: Whole Cells Applications: Control Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation. Species: Mouse Sample Types: In Vivo Applications: Control Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells. Species: Mouse Sample Types: Cell Lysates Applications: Control Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor.

Cancer, ; 6 Species: Mouse Sample Types: In Vivo Applications: Control Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha. J Invest Dermatol, ; 7 Invest Ophthalmol Vis Sci, ;55 2 PLoS Pathog, ;9 12 :e J Cell Biol, ; 1 Cancer Res, ;73 24 Mucosal Immunol, ;7 3 Dev Biol, ; 2 J Allergy Clin Immunol, ; 1 J Biol Chem, ; 30 Elife, ;2 0 :e Respir Res, ;14 0 J Exp Med, ; 2 Immunology, ; 2 Arterioscler Thromb Vasc Biol, ;33 4 Nat Commun, ;3 0 J Biol Chem, ; 3 Infect Immun, ;80 12 Am J Pathol, ; 5 J Invest Dermatol, ; 1 J Leukoc Biol, ;92 4 Immunity, ;35 6 PLoS Pathog.

Brain Behav. Lung Cell Mol. Cancer Prev Res Phila , ;3 10 Blood, ; 22 Blood, ; 2 Allergy Clin. Mucosal Immunol, ;3 1 Cancer, ; 6 Bone, ;44 5 Arthritis Rheum. Blood, ; 8 Glia, ;56 7 Endocrinology, ; 5 Care Med. Heart Circ. Blood, ; 1 Blood, ; 11 Cancer Res. Surgery, ; 1 Cell Res. Blood, ;99 3 A ul volume of 10ug Normal Goat IgG was injected intravenously every other day starting at day 13 post MOG for a total of 4 injections. Clinical scores were measured daily using the following scoring scale: 0 Normal mouse; no overt signs of disease; 1 Limp tail or hind limb weakness; 2 Limp tail and hind limb weakness; 3 Partial hind limb paralysis; 4 Complete hind limb paralysis; 5 Moribund state; death by EAE.


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Need help? Read the Bioinformatics Tool Guide for instructions on using this tool. Cleavage Blogs on IgG. Check out the latest blog posts on IgG. CD16A exists as a heterooligomeric polypeptide-anchored form in macrophages and NK cells Read full blog post. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest. Skip to main content. Support: Items in Cart 0.

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